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B5 protein domain
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B5 protein domain : ウィキペディア英語版
B5 protein domain

In molecular biology, Domain B5 is found in phenylalanine-tRNA synthetase beta subunits. This domain has been shown to bind DNA through a winged helix-turn-helix motif. Phenylalanine-tRNA synthetase may influence common cellular processes via DNA binding, in addition to its aminoacylation function.
==Function==
The beta domain, in particular, B5, is required for the correct amino acid to be joined to the corresponding tRNA. Hence, the B5 domain is crucial to accurate translation. Failure to do so, results in a mutated protein which improperly folds and consequently protein function is affected.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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